About: Phenytoin Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Phenytoin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Phenytoin Sodium
NSC_Code
  • 8722
UMLS_CUI
  • C0237417
CAS_Registry
  • 630-93-3
FDA_UNII_Code
  • 4182431BJH
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat or prevent seizures or convulsions that may be caused by epilepsy, brain surgery, or treatment for brain cancer. It is a type of anticonvulsant agent.NCI-GLOSS
Chemical_Formula
  • C15H11N2O2.Na
Legacy_Concept_Name
  • Phenytoin_Sodium
FULL_SYN
  • PHENYTOIN SODIUMPTFDA4182431BJH
  • Phenytoin SodiumPTNCI
  • DilantinSYDTPNSC0008722
  • DilantinPTNCI-GLOSSCDR0000658859
  • DilantinBRNCI
  • phenytoin sodiumPTNCI-GLOSSCDR0000658858
  • 5,5-Diphenyl-2,4-imidazolidinedione, Monosodium SaltSNNCI
DEFINITION
  • The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity.NCI
code
  • C48011
is Has_Salt_Form of
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