About: Chlorhexidine Gluconate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Chlorhexidine Gluconate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Chlorhexidine Gluconate
UMLS_CUI
  • C0055361
CAS_Registry
  • 18472-51-0
FDA_UNII_Code
  • MOR84MUD8E
Contributing_Source
  • FDA
Chemical_Formula
  • C22H30Cl2N10.2C6H12O7
Legacy_Concept_Name
  • Chlorhexidine_Gluconate
CHEBI_ID
  • CHEBI:28312
FULL_SYN
  • Chlorhexidine GluconatePTNCI
  • CHLORHEXIDINE GLUCONATEPTFDAMOR84MUD8E
DEFINITION
  • The gluconate salt form of chlorhexidine, a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine gluconate is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine gluconate penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent.NCI
code
  • C47974
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