About: Cefamandole Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefamandole Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefamandole Sodium
UMLS_CUI
  • C1707322
CAS_Registry
  • 30034-03-8
FDA_UNII_Code
  • IY6234ODVR
Contributing_Source
  • FDA
Chemical_Formula
  • C18H17N6O5S2.Na
Legacy_Concept_Name
  • Cefamandole_Sodium
FULL_SYN
  • Cefamandole SodiumPTNCI
  • CEFAMANDOLE SODIUMPTFDAIY6234ODVR
  • D-7-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Monosodium SaltSNNCI
DEFINITION
  • The sodium salt form of cefamandole, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C47967
is Has_Salt_Form of
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