About: Aminosalicylate Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Aminosalicylate Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Aminosalicylate Sodium
UMLS_CUI
  • C0301336
CAS_Registry
  • 6018-19-5
FDA_UNII_Code
  • S38B9W6AXW
Contributing_Source
  • FDA
Chemical_Formula
  • C7H6NO3.Na.2H2O
Legacy_Concept_Name
  • Aminosalicylate_Sodium
FULL_SYN
  • Aminosalicylate SodiumPTNCI
  • AMINOSALICYLATE SODIUMPTFDAS38B9W6AXW
  • Pamisyl SodiumSYNCI
  • TeebacinBRNCI
DEFINITION
  • The sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylate sodium exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death.NCI
code
  • C47958
is Has_Salt_Form of
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