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AttributesValues
rdf:type
rdfs:label
  • Travoprost
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Travoprost
UMLS_CUI
  • C0937916
CAS_Registry
  • 157283-68-6
Accepted_Therapeutic_Use_For
  • Glaucoma
FDA_UNII_Code
  • WJ68R08KX9
Contributing_Source
  • FDA
Chemical_Formula
  • C26H35F3O6
Legacy_Concept_Name
  • Travoprost
CHEBI_ID
  • CHEBI:746859
FULL_SYN
  • TravoprostPTNCI
  • AL-6221CNNCI
  • TRAVOPROSTPTFDAWJ68R08KX9
  • Travatan ZBRNCI
  • 5-Heptenoic Acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl Ester,(5Z)-SNNCI
DEFINITION
  • A synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure.NCI
code
  • C47766
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