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AttributesValues
rdf:type
rdfs:label
  • Telmisartan
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Telmisartan
UMLS_CUI
  • C0248719
CAS_Registry
  • 144701-48-4
FDA_UNII_Code
  • U5SYW473RQ
Contributing_Source
  • FDA
Chemical_Formula
  • C33H30N4O2
Legacy_Concept_Name
  • Telmisartan
CHEBI_ID
  • CHEBI:9434
FULL_SYN
  • TelmisartanPTNCI
  • TelmisartanSYNCI
  • 4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic AcidSNNCI
  • TelmisartanPTDCP32064
  • BIBR 277CNNCI
  • MicardisBRNCI
  • (1,1'-Biphenyl)-2-carboxylic Acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-SNNCI
  • TELMISARTANPTFDAU5SYW473RQ
DEFINITION
  • A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.NCI
code
  • C47746
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