About: Pergolide Mesylate

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Attributes	Values
rdf:type	Class
rdfs:label	Pergolide Mesylate
rdfs:subClassOf	ANTIPARKINSON AGENTS Dopamine Agonist
Has_Free_Acid_Or_Base_Form	PERGOLIDE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Pergolide Mesylate
NSC_Code	319773
UMLS_CUI	C0701027
CAS_Registry	66104-23-2
FDA_UNII_Code	55B9HQY616
Contributing_Source	FDA
Chemical_Formula	C19H26N2S.CH4O3S
Legacy_Concept_Name	Pergolide_Mesylate
CHEBI_ID	CHEBI:8021
FULL_SYN	8beta-[(Methylthio)methyl]-6-propylergoline MonomethanesulfonateSNNCI PermaxBRNCI Ergoline, 8-((Methylthio)Methyl)-6-Propyl-, Monomethanesulfonate, (8.Beta.)-SNNCI Pergolide MesylatePTNCI PERGOLIDE MESYLATEPTFDA55B9HQY616 LY127809CNNCI
DEFINITION	A semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor subtypes D1 and D2, resulting in prolactin secretion inhibition, transient increase in serum concentration of growth hormone, and decrease in serum concentration of luteinizing hormone. Direct stimulation of postsynaptic dopamine receptors in the nigrostriatal system, may account for this agent's antiparkinson activity.NCI
code	C47665
is Has_Salt_Form of	PERGOLIDE

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