About: Paromomycin Sulfate

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Paromomycin Sulfate
rdfs:subClassOf	AMINOGLYCOSIDES
Has_Free_Acid_Or_Base_Form	PAROMOMYCIN
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Paromomycin Sulfate
NSC_Code	227228
UMLS_CUI	C0733821
CAS_Registry	1263-89-4
FDA_UNII_Code	845NU6GJPS
Contributing_Source	FDA
Chemical_Formula	C23H45N5O14.H2SO4
Legacy_Concept_Name	Paromomycin_Sulfate
CHEBI_ID	CHEBI:7935
FULL_SYN	Humycin sulfateSYNCI HumatinBRNCI D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-beta-D-ribofuranosyl-(1->5))-2-deoxy-, Sulfate(salt)SNNCI Aminosidine SulfateSYNCI Paromomycin SulfatePTNCI PAROMOMYCIN SULFATEPTFDA845NU6GJPS
DEFINITION	The sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with amebicidal and bactericidal effects against predominantly aerobic gram-negative bacteria. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed by cell death.NCI
code	C47652
is Has_Salt_Form of	PAROMOMYCIN

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