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AttributesValues
rdf:type
rdfs:label
  • Oxtriphylline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Oxtriphylline
UMLS_CUI
  • C0055578
CAS_Registry
  • 4499-40-5
FDA_UNII_Code
  • 3K045XR58X
Contributing_Source
  • FDA
Chemical_Formula
  • C7H7N4O2.C5H14NO
Legacy_Concept_Name
  • Oxtriphylline
FULL_SYN
  • OXTRIPHYLLINEPTFDA3K045XR58X
  • OxtriphyllinePTNCI
  • Zy 15061CNNCI
  • CholedylBRNCI
  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione(1:1)SNNCI
  • Choline, hydroxide, compound with Theophylline(1:1)SYNCI
DEFINITION
  • The choline salt of theophylline with an anti-asthmatic property. Oxtriphylline appears to inhibit phosphodiesterase and prostaglandin production, regulates calcium flux and intracellular calcium distribution, and antagonizes adenosine. Physiologically, this agent causes relaxation of bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates cardiac muscle, as well as induces diuresis and gastric acid secretion. It may also suppress inflammation and improve contractility of the diaphragm.NCI
code
  • C47645
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