About: Isoxsuprine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Isoxsuprine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Isoxsuprine Hydrochloride
UMLS_CUI
  • C0282213
CAS_Registry
  • 579-56-6
FDA_UNII_Code
  • V74TEQ36CO
Contributing_Source
  • FDA
Chemical_Formula
  • C18H23NO3.HCl
Legacy_Concept_Name
  • Isoxsuprine_Hydrochloride
FULL_SYN
  • Isoxsuprine HydrochloridePTNCI
  • ISOXSUPRINE HYDROCHLORIDEPTFDAV74TEQ36CO
  • Norephedrine, p-hydroxy-N-(1-methyl-2-phenoxyethyl)-, HydrochlorideSNNCI
  • VasodilanBRNCI
  • 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 HydrochlorideSNNCI
DEFINITION
  • The hydrochloride salt of isoxsuprine, a benzyl alcohol derivative with vasodilator activity. The mechanism of action of isoxsuprine hydrochloride is controversial because this drug has beta-adrenergic agonist activities that are not reversed by beta-adrenergic blockers. Although stimulation of the beta adrenergic receptor increases blood flow to produce vasodilatation, this drug may also have direct effects on the contractility of smooth muscle. Isoxsuprine hydrochloride also causes relaxation of uterine smooth muscle and may also produce positive inotropic and chronotropic effects on the myocardium.NCI
code
  • C47576
is Has_Salt_Form of
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