About: Disopyramide Phosphate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Disopyramide Phosphate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Disopyramide Phosphate
UMLS_CUI
  • C0700534
CAS_Registry
  • 22059-60-5
FDA_UNII_Code
  • N6BOM1935W
Contributing_Source
  • FDA
Chemical_Formula
  • C21H29N3O.H3O4P
Legacy_Concept_Name
  • Disopyramide_Phosphate
CHEBI_ID
  • CHEBI:4658
FULL_SYN
  • Disopyramide PhosphatePTNCI
  • DISOPYRAMIDE PHOSPHATEPTFDAN6BOM1935W
  • 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium PhosphateSNNCI
  • alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide Phosphate(1:1)SNNCI
  • NorpaceBRNCI
  • RythmodanSYNCI
DEFINITION
  • A class Ia antiarrhythmic agent with cardiac depressant properties. Disopyramide phosphate exerts its actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential. This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues. Disopyramide prolongs the QT interval and causes a widening of the QRS complex. It also possesses some anticholinergic and local anaesthetic properties. Disopyramide phosphate is used in the treatment of supraventricular tachycardia.NCI
code
  • C47497
is Has_Salt_Form of
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