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AttributesValues
rdf:type
rdfs:label
  • Ceforanide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ceforanide
UMLS_CUI
  • C0055008
CAS_Registry
  • 60925-61-3
FDA_UNII_Code
  • 8M1YF8951V
Contributing_Source
  • FDA
Chemical_Formula
  • C20H21N7O6S2
Legacy_Concept_Name
  • Ceforanide
CHEBI_ID
  • CHEBI:3495
FULL_SYN
  • (6R-trans)-7-(((2-(Aminomethyl)phenyl)acetyl)amino)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic AcidSNNCI
  • PrecefSYNCI
  • CEFORANIDEPTFDA8M1YF8951V
  • CeforanidePTNCI
DEFINITION
  • A semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis.NCI
code
  • C47436
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