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AttributesValues
rdf:type
rdfs:label
  • Cabergoline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cabergoline
UMLS_CUI
  • C0107994
CAS_Registry
  • 81409-90-7
FDA_UNII_Code
  • LL60K9J05T
Contributing_Source
  • FDA
Chemical_Formula
  • C26H37N5O2
Legacy_Concept_Name
  • Cabergoline
CHEBI_ID
  • CHEBI:3286
FULL_SYN
  • CabergolinePTNCI
  • 1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylureaSNNCI
  • DostinexBRNCI
  • FCE 21336CNNCI
  • CABERGOLINEPTFDALL60K9J05T
DEFINITION
  • A synthetic ergoline derivative and a long-acting dopamine receptor agonist with high affinity for the dopamine D2 receptor. Cabergoline exerts an inhibitory effect on prolactin secretion by acting on dopamine receptors present in pituitary lactotrophs. This drug also binds to dopamine D2 receptors in the corpus striatum, thereby mimicking the actions of dopamine on motor control. Cabergoline also possesses antioxidant and neuroprotective properties due to its free radical scavenging activity. Cabergoline is used in the treatment of Parkinson's disease and in the treatment of hyperprolactinemia.NCI
code
  • C47428
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