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AttributesValues
rdf:type
rdfs:label
  • Butalbital
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Butalbital
NSC_Code
  • 9324
UMLS_CUI
  • C0054234
CAS_Registry
  • 77-26-9
FDA_UNII_Code
  • KHS0AZ4JVK
Contributing_Source
  • FDA
Chemical_Formula
  • C11H16N2O3
Legacy_Concept_Name
  • Butalbital
CHEBI_ID
  • CHEBI:102524
FULL_SYN
  • 5-Allyl-5-isobutylbarbituric AcidSNNCI
  • AllylbarbitalSYNCI
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-Methylpropyl)-5-(2-propenyl)-SNNCI
  • BUTALBITALPTFDAKHS0AZ4JVK
  • Allylbarbituric AcidSYNCI
  • OptalidonSYNCI
  • ButalbitalPTNCI
DEFINITION
  • A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence.NCI
code
  • C47425
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