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AttributesValues
rdf:type
rdfs:label
  • Bimatoprost
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bimatoprost
UMLS_CUI
  • C0937917
CAS_Registry
  • 155206-00-1
Accepted_Therapeutic_Use_For
  • Hypotrichosis of Eyelashes
FDA_UNII_Code
  • QXS94885MZ
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used under the name Latisse to increase the length, thickness, and darkness of eyelashes. It is being studied as a way to increase the growth of eyelashes and eyebrows in patients given chemotherapy for cancer. Bimatoprost is also used under the name Lumigan to treat glaucoma (a build-up of fluid in the eye). It lowers pressure in the eye by increasing the flow of natural eye fluids out of the eye. It is a type of prostaglandin analog.NCI-GLOSS
Chemical_Formula
  • C25H37NO4
Legacy_Concept_Name
  • Bimatoprost
CHEBI_ID
  • CHEBI:51230
FULL_SYN
  • BimatoprostPTNCI
  • bimatoprostPTNCI-GLOSSCDR0000666204
  • 5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-,(5Z)-SNNCI
  • LumiganPTNCI-GLOSSCDR0000675515
  • LatissePTNCI-GLOSSCDR0000666205
  • LumiganBRNCI
  • LatisseBRNCI
  • BIMATOPROSTPTFDAQXS94885MZ
  • AGN 192024CNNCI
DEFINITION
  • A synthetic prostamide and structural prostaglandin analogue with ocular hypotensive activity. Bimatoprost mimics the effects of the endogenous prostamides and reduces intraocular pressure by increasing outflow of aqueous humor through both the pressure-sensitive outflow pathway (the trabecular meshwork), and the pressure-insensitive outflow pathway (the uveoscleral routes). It is not clear whether bimatoprost lowers intraocular pressure by stimulating F-Prostanoid receptors or by acting on specific prostamide receptors.NCI
code
  • C47414
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