About: Alclometasone Dipropionate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Alclometasone Dipropionate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Alclometasone Dipropionate
UMLS_CUI
  • C0051113
CAS_Registry
  • 66734-13-2
FDA_UNII_Code
  • S56PQL4N1V
Contributing_Source
  • FDA
Chemical_Formula
  • C28H37ClO7
Legacy_Concept_Name
  • Alclometasone_Dipropionate
CHEBI_ID
  • CHEBI:31184
FULL_SYN
  • (7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dioneSNNCI
  • Alclometasone DipropionatePTNCI
  • VadermSYNCI
  • DelonalSYNCI
  • ALCLOMETASONE DIPROPIONATEPTFDAS56PQL4N1V
  • AclovateBRNCI
  • 7a-Chloro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione-17,21-dipropionateSNNCI
  • BRN 2317658CNNCI
DEFINITION
  • The dipropionate salt form of alclometasone, a synthetic corticosteroid with low to medium potency. Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids. This drug interacts with specific intracellular receptors and binds to DNA to modify gene expression. This results in an induction of synthesis of certain proteins while inhibiting the synthesis of others. Alclometasone dipropionate is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. (NCI05)NCI
code
  • C47385
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