About: Peutz-Jeghers Polyp     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Peutz-Jeghers Polyp
rdfs:subClassOf
equivalentClass
Semantic_Type
  • Disease or Syndrome
Preferred_Name
  • Peutz-Jeghers Polyp
UMLS_CUI
  • C0456487
Legacy_Concept_Name
  • Peutz-Jeghers_Polyp
FULL_SYN
  • Peutz Jeghers PolypSYNCI
  • Peutz-Jeghers PolypPTNCI
DEFINITION
  • A hamartomatous polyp that occurs in the stomach, small and large intestines, and rarely within the esophagus, nasopharynx and the urinary tract. The Peutz-Jeghers polyps are grossly lobulated and dark. Microscopically, they have a central core of smooth muscle covered by mucosa. The smooth muscle shows tree-like branching. The question of whether or not the Peutz-Jeghers polyp is precancerous is a matter of controversy. The loss of heterozygosity on chromosome 19p (where the responsible gene LKB1 is located) suggests that the increased risk of malignancy may be due to malignant transformation from hamartoma to adenocarcinoma. --2002NCI
code
  • C4733
is rdfs:subClassOf of
is someValuesFrom of
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