About: Phenoxybenzamine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Phenoxybenzamine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Hazardous or Poisonous Substance
Preferred_Name
  • Phenoxybenzamine Hydrochloride
NSC_Code
  • 37448
UMLS_CUI
  • C0701367
CAS_Registry
  • 63-92-3
FDA_UNII_Code
  • X1IEG24OHL
Contributing_Source
  • FDA
Chemical_Formula
  • C18H22ClNO.HCl
Legacy_Concept_Name
  • Phenoxybenzamine
FULL_SYN
  • N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine HydrochlorideSNNCI
  • Phenoxybenzamine HydrochloridePTDCP06063
  • DibenzylineBRNCI
  • PHENOXYBENZAMINE HYDROCHLORIDEPTFDAX1IEG24OHL
  • Phenoxybenzamine HydrochloridePTNCI
DEFINITION
  • The hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.NCI
code
  • C44435
is Has_Salt_Form of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 39 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software