About: Mantle Cell Lymphoma     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Mantle Cell Lymphoma
equivalentClass
Concept_In_Subset
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Mantle Cell Lymphoma
UMLS_CUI
  • C0334634
Contributing_Source
  • CTEP
ALT_DEFINITION
  • An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that usually occurs in middle-aged or older adults. It is marked by small- to medium-size cancer cells that may be in the lymph nodes, spleen, bone marrow, blood, and gastrointestinal system.NCI-GLOSS
ICD-O-3_Code
  • 9673/3
Neoplastic_Status
  • Malignant
Legacy_Concept_Name
  • Mantle_Cell_Lymphoma
FULL_SYN
  • Mantle cell lymphomaPTCTEP10026799
  • MCLABNCI
  • Mantle Cell LymphomaSYNCITCGA
  • mantle cell lymphomaPTNCI-GLOSSCDR0000445048
  • Mantle Cell LymphomaPTNCI
  • Mantle Zone LymphomaSYNCI
DEFINITION
  • An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.NCI
code
  • C4337
is rdf:first of
is someValuesFrom of
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