About: Monoclonal Antibody Bombesin-DTPA     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Monoclonal Antibody Bombesin-DTPA
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Monoclonal Antibody Bombesin-DTPA
OLD_PARENT
  • Monoclonal_Antibody
OLD_KIND
  • Chemicals_and_Drugs_Kind
OLD_ROLE
  • Chemical_Or_Drug_Affects_Gene_Product|Bombesin-Like_Receptor-3
  • Chemical_or_Drug_Has_Mechanism_Of_Action|Antigen_Binding_Interaction
  • Chemical_or_Drug_Has_Physiologic_Effect|Receptor_Inhibition
  • Chemical_Or_Drug_Affects_Gene_Product|Gastrin_Releasing_Peptide
  • Chemical_or_Drug_Has_Physiologic_Effect|Antigen_Targeting
Concept_Status
  • Retired_Concept
FULL_SYN
  • Monoclonal Antibody Bombesin-DTPAPTNCI
DEFINITION
  • A monoclonal antibody directed against the neurohormone bombesin that is conjugated to diethylenetriaminepenta-acetic acid (DPTA), a bifunctional chelating agent that allows the antibody to be labeled with a metal species such as radioactive indium. Levels of bombesin, also known as gastrin releasing peptide (GRP), are elevated in lung and thyroid cancers, where the substance acts as an autocrine growth factor. (NCI04)NCI
DesignNote
  • Merged with MoAb Bombesin (DTPA) C29212
code
  • C42055
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