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AttributesValues
rdf:type
rdfs:label
  • Deferoxamine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Deferoxamine
NSC_Code
  • 527604
UMLS_CUI
  • C0011145
CAS_Registry
  • 70-51-9
FDA_UNII_Code
  • J06Y7MXW4D
Contributing_Source
  • FDA
ALT_DEFINITION
  • An iron-chelating agent that removes iron from tumors by inhibiting DNA synthesis and causing cancer cell death. It is used in conjunction with other anticancer agents in pediatric neuroblastoma therapy.NCI-GLOSS
Chemical_Formula
  • C25H48N6O8
Legacy_Concept_Name
  • Deferoxamine
CHEBI_ID
  • CHEBI:4356
FULL_SYN
  • DeferoxaminePTNCI
  • N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamidePTDCP09403
  • deferoxaminePTNCI-GLOSSCDR0000045388
  • N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamideSNNCI
  • DesferrioxamineSYNCI
  • DesferrioxamineSYDTPNSC0527604
  • 1-Amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(n-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosaneSNNCI
  • N-[5-[3-[5-Aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic AcidSNNCI
  • DEFEROXAMINEPTFDAJ06Y7MXW4D
DEFINITION
  • An iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and siderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys and in the feces via the bile. This agent does not readily bind iron from transferrin, hemoglobin, myoglobin or cytochrome. (NCI04)NCI
code
  • C416
is Has_Free_Acid_Or_Base_Form of
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