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AttributesValues
rdf:type
rdfs:label
  • Depurination
rdfs:subClassOf
Semantic_Type
  • Phenomenon or Process
Preferred_Name
  • Depurination
UMLS_CUI
  • C1158480
Legacy_Concept_Name
  • Depurination
FULL_SYN
  • DepurinationPTNCI
DEFINITION
  • Depurination involves cleavage of the N-glycosidic link between a purine base and the remaining deoxyribose portion of the effected nucleotide in DNA, leading to loss of the purine base while leaving the DNA backbone intact. Depurination must be enzymically repaired to ensure genetic stability; transversion mutations result from purine loss.NCI
code
  • C41574
is someValuesFrom of
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