About: Vulvar Squamous Cell Carcinoma     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Vulvar Squamous Cell Carcinoma
equivalentClass
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Vulvar Squamous Cell Carcinoma
UMLS_CUI
  • C0280856
Neoplastic_Status
  • Malignant
Legacy_Concept_Name
  • Vulvar_Squamous_Cell_Carcinoma
FULL_SYN
  • Epidermoid Carcinoma of the VulvaSYNCI
  • Epidermoid Cell Carcinoma of VulvaSYNCI
  • Squamous Cell Carcinoma of the VulvaSYNCI
  • Vulva Epidermoid CarcinomaSYNCI
  • Vulvar Epidermoid CarcinomaSYNCI
  • Epidermoid Cell Carcinoma of the VulvaSYNCI
  • Epidermoid Carcinoma of VulvaSYNCI
  • Vulva Squamous Cell CarcinomaSYNCI
  • Vulvar Squamous Cell CarcinomaPTNCI
  • Vulva Epidermoid Cell CarcinomaSYNCI
  • Squamous Cell Carcinoma of VulvaSYNCI
  • Vulvar Epidermoid Cell CarcinomaSYNCI
DEFINITION
  • An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumor giant cells. Risk factors for recurrence include advanced stage, tumor diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumor. (WHO, 2003)NCI
code
  • C4052
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