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AttributesValues
rdf:type
rdfs:label
  • Curcumin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Curcumin
NSC_Code
  • 32982
UMLS_CUI
  • C0010467
CAS_Registry
  • 458-37-7
In_Clinical_Trial_For
  • Advanced pancreatic cancer
FDA_UNII_Code
  • IT942ZTH98
Contributing_Source
  • FDA
ALT_DEFINITION
  • A yellow pigment of the spice turmeric that is being studied in cancer prevention.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43115
PDQ_Closed_Trial_Search_ID
  • 43115
Chemical_Formula
  • C21H20O6
Legacy_Concept_Name
  • Curcumin
CHEBI_ID
  • CHEBI:3962
FULL_SYN
  • (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dioneSNNCI
  • Turmeric YellowSYNCI
  • CURCUMINPTFDAIT942ZTH98
  • CurcuminSYDTPNSC0032982
  • DiferuloylmethaneSYNCI
  • curcuminPTNCI-GLOSSCDR0000046049
  • CurcuminPTNCI
  • C.I. 75300CNNCI
  • C.I. Natural Yellow 3SYNCI
  • CurcuminPTDCP00291
DEFINITION
  • A phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation of reactive-oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C. These effects may play a role in the agent's observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer. (NCI04)NCI
code
  • C401
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