About: Therapeutic Corticotropin-Releasing Factor     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Therapeutic Corticotropin-Releasing Factor
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Therapeutic Corticotropin-Releasing Factor
NCI_META_CUI
  • CL324578
CAS_Registry
  • 86784-80-7
FDA_UNII_Code
  • 305OE8862Y
Contributing_Source
  • FDA
Chemical_Formula
  • C208H344N60O63S2
Legacy_Concept_Name
  • Therapeutic_Corticotropin_Releasing_Factor
FULL_SYN
  • CFRABNCI
  • CORTICORELINPTFDA305OE8862Y
  • Therapeutic Corticotropin-Releasing FactorPTNCI
  • CorticorelinSYNCI
  • CorticoliberinSYNCI
  • Recombinant Human Corticotropin Releasing FactorSYNCI
DEFINITION
  • Any synthetic therapeutic agent which is chemically identical to or similar to the endogenous human corticotropin-releasing factor (hCRF). Synthesized in the hypothalamus, hCRF stimulates the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH). In cerebral edema, hCRF acts by impeding the flow of fluid from blood vessels into brain tissue, thereby decreasing edema and stabilizing intracranial pressure. This agent possesses anti-edema properties independent of adrenal gland function. (NCI05)NCI
code
  • C394
is rdfs:subClassOf of
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