About: TNFR1 Signaling Pathway

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Attributes	Values
rdf:type	Class
rdfs:label	TNFR1 Signaling Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	TNFR1 Signaling Pathway
UMLS_CUI	C1515165
BioCarta_ID	h_tnfr1Pathway
ALT_DEFINITION	TNFR1 (p55, CD120a) is the receptor for TNF-alpha and also will bind TNF-beta. Upon binding TNF-alpha a TNFR1+ cell is triggered to undergo apoptosis. This critical regulatory process is accomplished by activating the proteolytic caspase cascade that results in the degradation of many critical cellular proteins.BIOCARTA
Legacy_Concept_Name	TNFR1_Signaling_Pathway
FULL_SYN	TNFR1 Signaling PathwayPTNCI TNFR1 Signaling PathwayPTBIOCARTA
code	C39254
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