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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Prion Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Prion Pathway
UMLS_CUI
  • C1514452
BioCarta_ID
  • h_prionPathway
ALT_DEFINITION
  • Transmissible spongiform encephalopathy (TSE) is thought to result from the structural conversion of cellular prion protein, PrP(C), into a misfolded oligomeric form, PrP(Sc). PrP is a cell membrane GPI anchored glycoprotein that is expressed in most tissues and in high levels in the nervous system. Some likely cellular functions of PrP are (1) cell protection against oxidative stress, (2) induction of neuronal cell adhesion, neurite extension and maintenance, and (3) neuroprotective signaling through a cAMP/PKA-dependent pathway.BIOCARTA
Legacy_Concept_Name
  • Prion_Pathway
FULL_SYN
  • Prion PathwayPTNCI
  • Prion PathwayPTBIOCARTA
code
  • C39201
is someValuesFrom of
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