About: Methionine, Isoleucine, Threonine and Valine Degradation Pathway     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Methionine, Isoleucine, Threonine and Valine Degradation Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Methionine, Isoleucine, Threonine and Valine Degradation Pathway
UMLS_CUI
  • C1513193
BioCarta_ID
  • h_methioninepathway
ALT_DEFINITION
  • The carbon chains of methionine, isoleucine, threonine, and valine are broken down to produce succinyl-CoA, which feeds into the Citric Acid Cycle. Methionine donates its methyl group via S-adenosylmethionine to one of several acceptors and the four remaining carbons are the backbone of propionyl-CoA that is subsequently converted to succinyl-CoA. The transdeamination and decarboxylation of valine are followed by a series of steps resulting in the formation of propionyl-CoA. Isoleucine also undergoes transdeamination, followed by oxidative decarboxylation. These steps yield propionyl-CoA as well as acetyl-CoA. Deficiency in the steps that convert isoleucine to propionyl-CoA causes sudden unexplained infant death, Reye-like syndrome, cardiomyopathy, and skeletal myopathy.BIOCARTA
Legacy_Concept_Name
  • Methionine_Isoleucine_Threonine_and_Valine_Degradation_Pathway
FULL_SYN
  • Catabolic Pathways for Methionine, Isoleucine, Threonine and ValinePTBIOCARTA
  • Methionine, Isoleucine, Threonine and Valine Degradation PathwayPTNCI
code
  • C39151
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 122 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software