About: IL5 Signaling Pathway

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: IL5 Signaling Pathway Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	IL5 Signaling Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	IL5 Signaling Pathway
UMLS_CUI	C1512597
BioCarta_ID	h_il5Pathway
ALT_DEFINITION	IL-5 is an inflammatory signaling molecule that primarily stimulates eosinophil proliferation, maturation, and activation. Eosinophils are leukocytes involved in inflammatory responses that defend against parasites and cause some aspects of asthma, allergic reactions, and perhaps autoimmune disorders. The action of IL-5 begins with an immune response in tissues, such as activation of macrophages and T cells that secrete IL-1, IL-4, and IL-6. The immune response can lead to IL-5 secretion by T cells, eosinophils, and mast cells. Secreted IL-5 stimulates production and maturation of eosinophils in bone marrow that migrate to tissues in response to eotaxin and release factors that damage tissues, causing some of the undesirable consequences of inflammation. The receptor for IL-5 is a heterodimer of an alpha subunit that is required for IL-5 selective binding and a beta subunit that is also part of the IL-3 and GM-CSF receptors. Binding of IL-5 to the IL-5 receptor at the cell surface activates JAK/STAT signaling pathways that regulate transcription, proliferation, and differentiation.BIOCARTA
Legacy_Concept_Name	IL5_Signaling_Pathway
FULL_SYN	IL 5 Signaling PathwayPTBIOCARTA IL5 Signaling PathwayPTNCI
code	C39126
is someValuesFrom of	nodeID://b652787 nodeID://b653493 nodeID://b653516 nodeID://b681500 nodeID://b681649 nodeID://b681660 nodeID://b681671 nodeID://b681695 nodeID://b683454 nodeID://b683919 nodeID://b683942 nodeID://b683950 nodeID://b683964 nodeID://b712810

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 26 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software