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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dicer Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Dicer Pathway
UMLS_CUI
  • C1511895
BioCarta_ID
  • h_dicerPathway
ALT_DEFINITION
  • The degradation of endogenous mRNA in a sequence-specific manner can be induced by dsRNA [RNA interference (RNAi)], antisense transcription, or viral infection. In the current model for posttranscriptional gene silencing by RNAi, the ribonuclease III like enzyme Dicer processes dsRNA into small fragments (siRNA) of 21-25 nts. The siRNA is incorporated into the RNA-induced silencing complex (RISC), which targets and degrades the homologous mRNA. Most of the proteins in the RISC (with the exception of Ago2 and Dicer have not been identified) but likely contain endonuclease, helicase, exonuclease and homology scanning activity.BIOCARTA
Legacy_Concept_Name
  • Dicer_Pathway
FULL_SYN
  • Dicer PathwayPTNCI
  • Dicer PathwayPTBIOCARTA
code
  • C39050
is someValuesFrom of
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