About: High Affinity Interleukin-2 Receptor

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About: High Affinity Interleukin-2 Receptor Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	High Affinity Interleukin-2 Receptor
rdfs:subClassOf	Protein or Riboprotein Complex nodeID://b680021 nodeID://b680022 nodeID://b680023 nodeID://b680024
Semantic_Type	Receptor
Preferred_Name	High Affinity Interleukin-2 Receptor
UMLS_CUI	C0034819
Legacy_Concept_Name	High_Affinity_Interleukin-2_Receptor
FULL_SYN	Interleukin-2 ReceptorSYNCI High Affinity Interleukin-2 ReceptorPTNCI
DEFINITION	Expressed on T- and B-cells, human heterodimeric High Affinity Interleukin-2 Receptor consists of IL2RA and IL2RB subunits, associated with a common IL2RG chain, and mediates IL2 mitogenic signaling. Homodimeric IL2RA chains constitute a low-affinity non-signaling receptor, while homodimeric IL2RB chains produce a medium-affinity signaling receptor. IL2RG comprises a signaling component of many interleukin receptors (IL2, IL4, IL7, IL9, and IL15). (NCI)NCI
code	C38952
is someValuesFrom of	nodeID://b719343
is Has_Target of	SBIL-2 Transduced Autologous Tumor-Infiltrating Lymphocyte Recombinant Interleukin-2

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