About: Aminophosphonate Metabolism Pathway     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Aminophosphonate Metabolism Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Aminophosphonate Metabolism Pathway
UMLS_CUI
  • C1510872
KEGG_ID
  • map00440
ALT_DEFINITION
  • Natural products containing carbon-phosphorous bonds, so-called C-P compounds, are derivatives of phosphonate and phosphinate with substitution of alkyl group for hydrogen of phosphorus-hydrogen bonds. C-P compounds have been found in many organisms, but only protists and bacteria, mostly Actinobacteria, have biosynthetic capacity. A common reaction in the biosynthetic pathway is C-P bond forming reaction from phosphoenolpyruvate (PEP) to phosphonopyruvate (PnPy) catalyzed by PEP phosphomutase. 2-Aminoethylphosphonate (AEP) is the most abundant C-P compound in the natural world. AEP derivatives include phosphonoprotein, phosphonoglycan, and phosphonolipid. Other known C-P compounds are bioactive substances used in medicine (antibiotics) and agriculture (herbicide) such as fosfomycin, FR-33289, rhizocticin, and bialaphos.KEGG
Legacy_Concept_Name
  • Aminophosphonate_Metabolism_Pathway
FULL_SYN
  • Aminophosphonate Metabolism PathwayPTNCI
  • Aminophosphonate MetabolismSYKEGG
  • Phosphonate and phosphinate metabolismPTKEGG
code
  • C38780
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