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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Conjunctival Route of Administration
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Functional Concept
Preferred_Name
  • Conjunctival Route of Administration
UMLS_CUI
  • C1522483
FDA_Table
  • Route of Administration (C-DRG-00301)
Contributing_Source
  • CDISC
  • FDA
ALT_DEFINITION
  • Administration to the conjunctiva, the delicate membrane that lines the eyelids and covers the exposed surface of the eyeball. (FDA)CDISC
Legacy_Concept_Name
  • Conjunctival_Route_of_Drug_Administration
FULL_SYN
  • CONJUNCTIVALPTFDA068
  • CONJUNCTIVALPTFDA
  • ConjunctivalSYNCI
  • CONJUNCTIVALPTCDISC
  • Conjunctival Route of AdministrationPTNCI
  • CONJUNCABFDA068
  • CONJUNCABNCI
DEFINITION
  • Administration of a drug to the conjunctiva, the most frequently used mode of ocular drug delivery. Advantages of this topical route include direct, localized delivery to the target tissue, good accessibility into the intraocular environment owing to membrane permeability and large intercellular spaces, avoidance of hepatic first-pass metabolism, convenience, and relative painlessness. Limitations include rapid drug elimination due to lacrimation and nasolacrimal drainage, drug binding to, and metabolism by, tear proteins, and target non-specificity as a result of systemic absorption through the nasal mucosa and conjunctival vasculature.NCI
code
  • C38194
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