About: Buccal Route of Administration

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Attributes	Values
rdf:type	Class
rdfs:label	Buccal Route of Administration
rdfs:subClassOf	Oral Route of Administration
Concept_In_Subset	Structured Product Labeling Drug Route of Administration Terminology Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Route of Administration Terminology CDISC SDTM Terminology CDISC SEND Terminology
Semantic_Type	Functional Concept
Preferred_Name	Buccal Route of Administration
UMLS_CUI	C0521135
FDA_Table	Route of Administration (C-DRG-00301)
Contributing_Source	CDISC FDA
ALT_DEFINITION	Administration directed toward the cheek, generally from within the mouth. (FDA)CDISC
Legacy_Concept_Name	Buccal_Route_of_Drug_Administration
FULL_SYN	BUCCALABFDA030 BUCCALPTFDA030 BUCCABNCI BUCCALPTFDA BuccalSYNCI BUCCALPTCDISC Buccal Route of AdministrationPTNCI
DEFINITION	Administration of a substance through the mucosal membrane on the inside of the cheek or the back of the mouth. Buccal route bypasses first pass metabolism and avoids pre-systemic elimination in the gastrointestinal tract. The buccal environment is well supplied with both vascular and lymphatic drainage and is well suited for a retentive device. This is a feasible alternative for systemic delivery of orally inefficient drugs, such as peptide and protein drug molecules.NCI
code	C38193

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