About: NA17-A Antigen     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • NA17-A Antigen
rdfs:subClassOf
Semantic_Type
  • Immunologic Factor
Preferred_Name
  • NA17-A Antigen
UMLS_CUI
  • C1134655
In_Clinical_Trial_For
  • Metastatic melanoma
PDQ_Open_Trial_Search_ID
  • 38647
PDQ_Closed_Trial_Search_ID
  • 38647
Legacy_Concept_Name
  • NA17-A_Antigen
FULL_SYN
  • NA17-A AntigenPTNCI
  • NA17-ASYNCI
DEFINITION
  • A specific melanoma antigen protein derived from a patient (NA17) with cutaneous melanoma metastases. When administered in a vaccine formulation, NA17-A antigen may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size. The NA17-A antigen is part of the enzyme N-acetyl glucosaminyltransferase V (GnT-V). Approximately half of melanomas have been found to express significant levels of this atypical protein, which is not expressed by normal tissues.NCI
code
  • C37450
is someValuesFrom of
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