About: Chlorhexidine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Chlorhexidine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Chlorhexidine
UMLS_CUI
  • C0008196
CAS_Registry
  • 55-56-1
FDA_UNII_Code
  • R4KO0DY52L
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41544
PDQ_Closed_Trial_Search_ID
  • 41544
Chemical_Formula
  • C22H30Cl2N10
Legacy_Concept_Name
  • Chlorhexidine
CHEBI_ID
  • CHEBI:3614
FULL_SYN
  • CHLORHEXIDINEPTFDAR4KO0DY52L
  • ChlorhexidinePTNCI
DEFINITION
  • A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent.NCI
code
  • C364
is Has_Free_Acid_Or_Base_Form of
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