About: Gastrointestinal Tract Adenoma     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Gastrointestinal Tract Adenoma
equivalentClass
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Gastrointestinal Tract Adenoma
UMLS_CUI
  • C0948101
Neoplastic_Status
  • Benign
Legacy_Concept_Name
  • Gastrointestinal_Adenoma
FULL_SYN
  • Gastrointestinal AdenomaSYNCI
  • Gastrointestinal Tract AdenomaPTNCI
  • GI AdenomaSYNCI
DEFINITION
  • A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.NCI
code
  • C36207
is rdf:first of
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