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AttributesValues
rdf:type
rdfs:label
  • Cephalexin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cephalexin
UMLS_CUI
  • C0007716
CAS_Registry
  • 23325-78-2
FDA_UNII_Code
  • OBN7UDS42Y
Contributing_Source
  • FDA
ALT_DEFINITION
  • An antibiotic drug that belongs to the family of drugs called cephalosporins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43417
PDQ_Closed_Trial_Search_ID
  • 43417
Chemical_Formula
  • C16H17N3O4S.H2O
Legacy_Concept_Name
  • Cephalexin
CHEBI_ID
  • CHEBI:3535
FULL_SYN
  • cephalexinPTNCI-GLOSSCDR0000046205
  • KeflexBRNCI
  • CEPHALEXINPTFDAOBN7UDS42Y
  • CephalexinPTNCI
DEFINITION
  • A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms.NCI
code
  • C356
is Has_Free_Acid_Or_Base_Form of
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