About: Long QT Syndrome

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Attributes	Values
rdf:type	Class
rdfs:label	Long QT Syndrome
rdfs:subClassOf	Syndrome Non-Neoplastic Heart Disorder
Has_NICHD_Parent	Congenital Heart Disease
Concept_In_Subset	CDISC SDTM Sudden Death Syndrome Type Terminology Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology CDISC SDTM ECG Finding Terminology CDISC SEND Terminology NICHD Terminology Neonatal Research Network Terminology
Semantic_Type	Disease or Syndrome
Preferred_Name	Long QT Syndrome
UMLS_CUI	C0023976
Contributing_Source	CDISC NICHD
ALT_DEFINITION	A syndrome characterized by history of syncopal episodes and a long QT interval, sometimes leading to sudden death (DEATH, SUDDEN, CARDIAC) due to paroxysmal ventricular arrhythmia. A form associated with autosomal recessive inheritance and congenital deafness is called the JERVELL-LANGE NIELSEN SYNDROME. An autosomal dominant form without deafness is called the ROMANO-WARD SYNDROME.MSH2003_2003_05_12 Long QT Syndrome includes prolongation of the corrected QT interval beyond 440 ms for adult males, 460 ms for adult females and 50 ms in the presence of ventricular depolarization abnormalities (i.e., bundle branch blocks or IVCB more than 120 ms. A normal QT interval in a resting ECG with a failure to shorten with an increase in heart rate qualifies as Long QT Syndrome.CDISC A ventricular arrhythmia characterized by syncopal episodes and a long QT interval, sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarisation following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. (NCI)CSP2003
Legacy_Concept_Name	Long_QT_Syndrome
FULL_SYN	LONG QT SYNDROMEPTCDISCSDTM-SDTHSDTP Long QT SyndromePTNCI VENTRICULAR ARRHYTHMIA ASSOCIATED WITH LONG QT SYNDROMEPTCDISCSDTM-EGSTRESC Ventricular arrhythmia associated with long QT syndromeSYCDISC Long QT SyndromePTNICHD
DEFINITION	A ventricular arrhythmia characterized by syncopal episodes and a long QT interval, sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death.NCI
code	C34786
is rdfs:subClassOf of	Jervell-Lange Nielsen Syndrome Romano-Ward Syndrome
is someValuesFrom of	nodeID://b675960

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