About: Myelodysplastic Syndrome

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Attributes	Values
rdf:type	Class
rdfs:label	Myelodysplastic Syndrome
equivalentClass	nodeID://b635867
Concept_In_Subset	NCI CTEP Simplified Disease Classification Terminology NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology
Semantic_Type	Neoplastic Process
Preferred_Name	Myelodysplastic Syndrome
UMLS_CUI	C0033027
Contributing_Source	CTEP
ALT_DEFINITION	A group of diseases in which the bone marrow does not make enough healthy blood cells.NCI-GLOSS A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.CTCAE
ICD-O-3_Code	9989/3
Neoplastic_Status	Undetermined
Legacy_Concept_Name	Myelodysplastic_Syndrome
FULL_SYN	Myelodysplastic SyndromeSYNCITCGA PreleukemiaSYNCI Myelodysplastic Syndrome/NeoplasmSYNCI preleukemiaPTNCI-GLOSSCDR0000045480 Myelodysplastic NeoplasmSYNCI Dysmyelopoietic SyndromeSYNCI Myelodysplastic SyndromePTNCI myelodysplastic syndromesPTNCI-GLOSSCDR0000045266 MyelodysplasiaSYNCI MDSABNCI Myelodysplastic syndrome, NOSPTCTEP10028534 smoldering leukemiaPTNCI-GLOSSCDR0000046583 Hematopoeitic - Myelodysplastic Syndrome (MDS)SYNCI Myelodysplastic syndromePTCTCAEE12552 myelodysplasiaPTNCI-GLOSSCDR0000045953 Smoldering LeukemiaSYNCI Oligoblastic LeukemiaSYNCI
DEFINITION	A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)NCI
code	C3247
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is someValuesFrom of	nodeID://b644115 nodeID://b673070 nodeID://b693938 nodeID://b695710 nodeID://b696008 nodeID://b701394 nodeID://b717342

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