About: Non-Hodgkin Lymphoma

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About: Non-Hodgkin Lymphoma Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Non-Hodgkin Lymphoma
equivalentClass	nodeID://b636196
Concept_In_Subset	NCI CTEP Simplified Disease Classification Terminology NCI CTEP SDC Non-Hodgkin Lymphoma Sub-Category Terminology
Semantic_Type	Neoplastic Process
Preferred_Name	Non-Hodgkin Lymphoma
UMLS_CUI	C0024305
Contributing_Source	CTEP
ALT_DEFINITION	Any of a large group of cancers of lymphocytes (white blood cells). NHLs can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of NHL. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell NHLs include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell NHLs. Prognosis and treatment depend on the stage and type of disease.NCI-GLOSS
ICD-O-3_Code	9591/3
Neoplastic_Status	Malignant
Legacy_Concept_Name	Non-Hodgkin_s_Lymphoma
FULL_SYN	Non-Hodgkin's LymphomaSYNCI NHLPTNCI-GLOSSCDR0000430869 NHL, NOSSYCTEP10029593 NHLABNCI non-Hodgkin lymphomaPTNCI-GLOSSCDR0000045148 Non-Hodgkin's Lymphoma (NHL)SYNCI Non-Hodgkin lymphoma, NOSPTCTEP10029593 Non-Hodgkin LymphomaPTNCI
DEFINITION	Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.NCI
code	C3211
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