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AttributesValues
rdf:type
rdfs:label
  • Broxuridine
rdfs:subClassOf
equivalentClass
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Broxuridine
NSC_Code
  • 38297
UMLS_CUI
  • C0006233
CAS_Registry
  • 21597-77-3
  • 59-14-3
FDA_UNII_Code
  • G34N38R2N1
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that makes cancer cells more sensitive to radiation and is also used as a diagnostic agent to determine how fast cancer cells grow.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39168
PDQ_Closed_Trial_Search_ID
  • 39168
Chemical_Formula
  • C9H11BrN2O5
Legacy_Concept_Name
  • Bromodeoxyuridine
CHEBI_ID
  • CHEBI:472552
FULL_SYN
  • Bromouracil deoxyribosideSYDTPNSC0038297
  • BRDUSYDTPNSC0038297
  • BroxuridineSYDTPNSC0038297
  • BroxuridinePTNCI
  • 5-BromodeoxyuridineSYDTPNSC0038297
  • 5-Bromo-2'-deoxyuridineSNNCI
  • BromouridineSYNCI
  • 5-Bromouracil deoxyribosideSYDTPNSC0038297
  • broxuridinePTNCI-GLOSSCDR0000045179
  • 5-BudrSYDTPNSC0038297
  • Bromouracil DeoxyribosideSYNCI
  • BrdUABNCI
  • 5-Bromouracil-2-deoxyribosideSYDTPNSC0038297
  • 5-Bromouracil DeoxyribosideSNNCI
  • 5-Bromo-2'-deoxyuridineSYDTPNSC0038297
  • 5-BrdUABNCI
  • BromodeoxyuridineSYNCI
  • 5-Bromouracil-2-deoxyribosideSNNCI
  • NeomarkBRNCI
  • BroxineBRNCI
  • 5-BromodeoxyuridineSNNCI
  • BromodeoxyuridineSYDTPNSC0038297
  • BROXURIDINEPTFDAG34N38R2N1
  • Neomark-BUBRNCI
DEFINITION
  • A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks.NCI
code
  • C318
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