About: Langerhans Cell Histiocytosis     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Langerhans Cell Histiocytosis
equivalentClass
Has_NICHD_Parent
Concept_In_Subset
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Langerhans Cell Histiocytosis
UMLS_CUI
  • C0019621
Contributing_Source
  • CTEP
  • NICHD
ALT_DEFINITION
  • A group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain tissues and organs including the bones, skin, and lungs, and damage them. Langerhans cell histiocytosis may also affect the pituitary gland (which makes hormones that control other glands and many body functions, especially growth). Langerhans cell histiocytosis is most common in children and young adults.NCI-GLOSS
ICD-O-3_Code
  • 9751/1
  • 9751/3
  • 9752/1
  • 9753/1
  • 9754/3
Neoplastic_Status
  • Undetermined
Legacy_Concept_Name
  • Langerhans_Cell_Histiocytosis
FULL_SYN
  • LCHPTNCI-GLOSSCDR0000513054
  • Histiocytic SyndromeSYNICHD
  • LCHABNCI
  • Langerhans cell histiocytosisPTCTEP10025581
  • Histiocytosis XSYNCI
  • HistiocytosisPTNICHD
  • Langerhans Cell HistiocytosisSYNCITCGA
  • Langerhans Cell HistiocytosisPTNCI
  • Langerhans Cell GranulomatosisSYNCI
  • Langerhans cell histiocytosisPTNCI-GLOSSCDR0000471787
DEFINITION
  • A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001)NCI
code
  • C3107
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