About: Interferon Alfa-N3     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Interferon Alfa-N3
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Interferon Alfa-N3
UMLS_CUI
  • C1621234
CAS_Registry
  • 9008-11-1
Legacy_Concept_Name
  • Interferon_Alfa-N3
FULL_SYN
  • Alfa-N3 InterferonSYNCI
  • Interferon Alfa-N3PTNCI
  • AltemolFBNCI
  • Alferon NBRNCI
DEFINITION
  • A formulated therapeutic analog of the endogenous alpha interferon containing multiple interferon species with antiviral and antitumor properties. Interferons bind to specific cell-surface receptors, leading to the transcription and translation of genes with an interferon-specific response element, thereby inducing: antiviral effects (the most important being inhibition of viral protein synthesis); antiproliferative effects (including inhibition of cellular growth and alteration of cellular differentiation); anticancer effects (including interference with oncogene expression); and immune-modulating effects (including activation of natural killer cells, alteration of cell surface antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04)NCI
code
  • C30136
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