About: 60S Ribosomal Protein L7a     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • 60S Ribosomal Protein L7a
equivalentClass
OMIM_Number
  • 185640
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • 60S Ribosomal Protein L7a
UMLS_CUI
  • C0073263
Legacy_Concept_Name
  • Ribosomal_Protein-L7A
FULL_SYN
  • Thyroid Hormone Receptor Uncoupling ProteinSYNCI
  • Surfeit Locus Protein 3SYNCI
  • 60S Ribosomal Protein L7aPTNCI
  • TRUPSYNCI
  • RPL7ASYNCI
  • SURF3SYNCI
  • PLA-X PolypeptideSYNCI
  • Surfeit 3SYNCI
  • Ribosomal Protein L7aSYNCI
Swiss_Prot
  • P11518
DEFINITION
  • Encoded by human RPL7A Gene (L7AE Family), 265-aa 30-kDa Ribosomal Protein L7a is a component of the large 60S ribosomal subunit. Composed of small 40S and large 60S subunits containing 4 rRNAs and approximately 80 proteins, ribosomes catalyze protein synthesis. RPL7A can inhibit a subclass of transactivating nuclear hormone receptors, including THR, by preventing DNA binding. Gene rearrangements with TRK form TRK-2H, which encodes an oncoprotein of the RPL7A N terminus fused to the TRK tyrosine kinase domain. (NCI)NCI
code
  • C29903
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