About: Sulfonamide Anti-Infective Agent

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Attributes	Values
rdf:type	Class
rdfs:label	Sulfonamide Anti-Infective Agent
rdfs:subClassOf	Anti-infective Agent
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Sulfonamide Anti-Infective Agent
UMLS_CUI	C0038760
ALT_DEFINITION	A type of antibiotic used to treat infection.NCI-GLOSS
Legacy_Concept_Name	Sulfonamide_Anti-infective_Agent
FULL_SYN	Sulfonamide Anti-Infective AgentPTNCI sulfa drugPTNCI-GLOSSCDR0000367475 SulfonamidesSYNCI sulfonamidePTNCI-GLOSSCDR0000367474
DEFINITION	A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis.NCI
code	C29739
is rdfs:subClassOf of	SULFACETAMIDE SODIUM SULFADIAZINE SULFACYTINE SULFAMETHIZOLE SULFAMETHOXAZOLE SULFISOXAZOLE SULFAMERAZINE SULFAMETHAZINE SULFACETAMIDE Sulfadiazine Sodium Silver Sulfadiazine Sulfameter SULFATHIAZOLE Salazosulfamide Salazosulfathiazole Succisulfone Sulfachrysoidine Salazosulfadimidine Sulfametrole Sulfamonomethoxine Vanyldisulfamide Sulfamazone Sulfapyridine Sodium Maleylsulfathiazole Phthalylsulfamethizole Sulfachlorpyridazine Sulfadimethoxine Sulfadimethoxine Sodium Sulfaguanidine Sulfanitran Sulfaquinoxaline Sulfasomizole Sulfasuccinamide Sulfathiourea Phthalylsulfacetamide Phthalylsulfathiazole Solasulfone Sulfamerazine Sodium Sulfamethoxypyridazine SULFANILAMIDE SULFISOXAZOLE ACETYL Ditolamide Sulfaphenazole SULFAPYRIDINE SULFISOXAZOLE DIOLAMINE Sulfoxone Sodium Sulfaclomide Sulfaguanole Sulfametomidine Sulfaperin Sulfaproxyline Sulfoxone Stearylsulfamide Sulfaclorazole Sulfatrozole Acetyl Sulfamethoxypyridazine Sulfabromomethazine Sulfalene Glucosulfamide Sulfamethazine Sodium Sulfabromomethazine Sodium SULFABENZAMIDE Sulfamethazine Bisulfate Sulfamidochrysoidine

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