About: Alpha-Adrenergic Antagonist

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Attributes	Values
rdf:type	Class
rdfs:label	Alpha-Adrenergic Antagonist
rdfs:subClassOf	Adrenergic Antagonist
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Alpha-Adrenergic Antagonist
UMLS_CUI	C0001641
ALT_DEFINITION	A substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of urine and blood. Alpha-blockers are used to treat the symptoms of many conditions, such as benign prostatic hyperplasia (BPH), high blood pressure, and some blood circulation problems.NCI-GLOSS
Legacy_Concept_Name	Alpha-adrenergic_Blocking_Agent
CHEBI_ID	CHEBI:37890
FULL_SYN	Alpha BlockerSYNCI alpha-blockerPTNCI-GLOSSCDR0000651173 Alpha-Adrenergic AntagonistPTNCI alpha-adrenergic antagonistPTNCI-GLOSSCDR0000651174 Alpha-adrenergic Blocking AgentSYNCI
DEFINITION	Natural or synthetic Alpha-adrenergic Blocking Agents selectively bind to adrenergic receptors, or compete with natural adrenergic mediators, and inactivate alpha adrenergic receptors of the sympathetic nervous system. These agents block the action of natural sympathomimetic neurotransmitters (norepinephrine and related substances), and can initiate physiological responses such as vasodilation, bradycardia, and pupil contraction.NCI
code	C29713
is rdfs:subClassOf of	TAMSULOSIN HYDROCHLORIDE Terazosin Hydrochloride PHENTOLAMINE MESYLATE Phenoxybenzamine Hydrochloride TERAZOSIN PHENOXYBENZAMINE PHENTOLAMINE LABETALOL HYDROCHLORIDE TOLAZOLINE TOLAZOLINE HYDROCHLORIDE Quinazosin Naftopidil TAMSULOSIN Terazosin Hydrochloride Anhydrous Tinazoline Tolboxane Phentolamine Hydrochloride Napamezole Hydrochloride Zolertine Zolertine Hydrochloride Napitane Nicergoline Moxisylyte Moxisylyte Hydrochloride Tibalosin Tymazoline PRAZOSIN HYDROCHLORIDE Doxazosin Mesylate Bretylium Tosylate DAPIPRAZOLE HYDROCHLORIDE Alfuzosin Hydrochloride ALFUZOSIN DOXAZOSIN DIHYDROERGOTOXINE Fiduxosin Fipamezole Piperoxan Taprizosin Abanoquil Aceperone Esproquin Esproquin Hydrochloride Atipamezole Bunazosin Efaroxan Tiodazosin Butanserin Spiroxatrine Azaloxan Azapetine Phosphate Debrisoquin Fadolmidine Trimazosin Trimazosin Hydrochloride Upidosin YOHIMBINE HYDROCHLORIDE Dihydro-alpha-Ergocryptine Dihydro-alpha-Ergocryptine Mesylate Epicriptine Dihydro-beta-Ergocryptine Mesylate DIHYDROERGOCORNINE DIHYDROERGOCORNINE MESYLATE DIHYDROERGOCRISTINE DIHYDROERGOCRISTINE MESYLATE PRAZOSIN Atiprosin BRETYLIUM Bunazosin Hydrochloride Debrisoquin Sulfate Deriglidole YOHIMBINE Atipamezole Hydrochloride Piperoxan Hydrochloride Fiduxosin Hydrochloride SILODOSIN Azapetine Azapetine Hydrochloride DAPIPRAZOLE Guanazodine Idralfidine Ifenprodil Imiloxan Imiloxan Hydrochloride Napamezole

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