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AttributesValues
rdf:type
rdfs:label
  • Triaminic Syrup
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Triaminic Syrup
UMLS_CUI
  • C0247499
Legacy_Concept_Name
  • Triaminic_Syrup
FULL_SYN
  • Triaminic SyrupPTNCI
DEFINITION
  • Any of the commercial combination preparations, by Novartis, that is taken orally as syrup containing all or a combination of the following agents: the analgesic antipyretic acetaminophen, the antihistamine chlorpheniramine maleate, the antitussive dextromethorphan hydrobromide and the decongestant pseudoephedrine hydrochloride. The particular combination depends on the symptoms that need to be treated such as cough, congestion, fever, allergy and sore throat. Acetaminophen exerts its actions by inhibiting prostaglandin synthesis. Chlorpheniramine maleate blocks the effects of histamine. Dextromethorphan hydrobromide raises the threshold for coughing in the cough center. Pseudoephedrine, a sympathomimetic agent, causes vasoconstriction mediated through alpha-adrenergic receptors, thereby reducing blood flow which decreases swelling and prevents nasal and sinus congestion.NCI
code
  • C29518
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