About: Potassium Citrate

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Attributes	Values
rdf:type	Class
rdfs:label	Potassium Citrate
rdfs:subClassOf	Electrolyte Replacement Agent
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Potassium Citrate
UMLS_CUI	C0137996
CAS_Registry	6100-05-6
FDA_UNII_Code	EE90ONI6FF
Contributing_Source	FDA
Chemical_Formula	C6H5O7.3K.H2O
Legacy_Concept_Name	Potassium_Citrate
CHEBI_ID	CHEBI:64746
FULL_SYN	2-Hydroxy-1,2,3-propanetricarboxylic Acid, Potassium SaltSNNCI Potassium CitratePTNCI POTASSIUM CITRATEPTFDAEE90ONI6FF 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Potassium SaltPTDCP00860
DEFINITION	The potassium salt form of citrate with alkalinizing property. Following absorption, potassium citrate causes increased plasma bicarbonate concentration, thereby raising blood and urinary pH. A simultaneous decrease in calcium ion activity occurs as a result of increasing calcium complex formation with dissociated anions. Levels of urinary citrate are increased due to modification of the renal handling of citrate. By promoting excretion of free bicarbonate ion and by increasing urinary pH in addition to an increased ionization of uric acid to more soluble urate ions, this agent exerts the alkalizing and anti-urolithic effect.NCI
code	C29372

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