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AttributesValues
rdf:type
rdfs:label
  • Phenylpropanolamine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Phenylpropanolamine
NSC_Code
  • 17704
  • 9920
UMLS_CUI
  • C0031495
CAS_Registry
  • 14838-15-4
  • 492-41-1
FDA_UNII_Code
  • 33RU150WUN
Contributing_Source
  • FDA
Chemical_Formula
  • C9H13NO
Legacy_Concept_Name
  • Phenylpropanolamine
FULL_SYN
  • PhenylpropanolaminePTNCI
  • PHENYLPROPANOLAMINEPTFDA33RU150WUN
DEFINITION
  • An alpha- and beta-adrenergic receptor agonist with sympathomimetic activity. Phenylpropanolamine (PPA) binds to and activates alpha- and beta-adrenergic receptors in the mucosa of the respiratory tract resulting in vasoconstriction and reduction in swelling of nasal mucous membranes and reduction in tissue hyperemia, edema, and nasal congestion. This agent also stimulates the release of norepinephrine from its storage sites resulting in the effects already described. Finally, PPA indirectly stimulates beta-receptors producing tachycardia and a positive inotropic effect.NCI
code
  • C29364
is Has_Free_Acid_Or_Base_Form of
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